Definition and explanation
Relevance is the extent to which the body of evidence from the primary studies supporting a review finding is applicable to the context specified in the review question. This may relate to, for example, the perspective or population researched, the phenomenon of interest or the setting.
Relevance is important in assessing confidence as it indicates to the end user the extent to which the contexts of the primary studies contributing evidence to a finding are aligned with the context specified in the review question. When the contexts of the primary studies underlying a review finding are substantively different from the context of the review question, we are less confident that the review finding reflects the phenomenon of interest.